SAFETY ASSESSMENT OF SOYBEANS EXPOSED TO GLYPHOSATE USING IN VIVO ASSAY

Autores

  • Edith Alba Segovia Corrales Universidad Nacional de Asunción - Paraguay
  • Romina Arrua Universidad Nacional de Asunción - Paraguay
  • Hajime Kurita Universidad Nacional de Asunción - Paraguay
  • Rosa Oviedo de Cristaldo Universidad Nacional de Asunción - Paraguay
  • Lider Ayala Universidad Nacional de Asunción - Paraguay

DOI:

https://doi.org/10.56067/saetauniversitaria.v13i2.462

Palavras-chave:

Chromosome Aberration, Micronucleus, Soybean, Genetically Modified Organism

Resumo

Soybean (Glycine max (L.) merrill) is the main economic crop in Paraguay, where conventional and/or transgenic varieties are planted. Possible side effects of GM soy are still under discussion The aim of this study was to evaluate the mutagenic effect of three varieties of soybean two transgenic BRS 245 RR; Nueva Andrea 66R (T1, T2) and a conventional BRS 232 (T3) exposed to Glyphosate in the diet of mice using in vivo trials. Methods: tests were carried out in a murine model. Two trials were performed, first feeding BALB/C mice for 14 days and 42 days with T1 and T3, then feeding Swiss albino mice for 14 days with T2 and T3. Treatments were done in two groups: without glyphosate (G0) and with glyphosate (G1). The animals treated for 14 days were tested for Micronucleus and the animals treated for 42 days were tested for Micronucleus and Chromosomal Aberration. Results: Both trials had no mutagenic effects in mice. It is concluded that the soybean varieties evaluated did not present mutagenic effects (aneugenic or clastogenic) under these experimental conditions.

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Biografia do Autor

Edith Alba Segovia Corrales, Universidad Nacional de Asunción - Paraguay

Bióloga, MSc, PhD. (Universidad Nacional de Asunción, Paraguay). edith .segovia@cemit.una.py

Romina Arrua, Universidad Nacional de Asunción - Paraguay

Bióloga. (Universidad Nacional de Asunción. Paraguay). romyarrua@gmail.com

Hajime Kurita, Universidad Nacional de Asunción - Paraguay

Biólogo, MSc, PhD. (Universidad Nacional de Asunción. Paraguay). haguiku@hotmail.com

Rosa Oviedo de Cristaldo, Universidad Nacional de Asunción - Paraguay

Ing. Agr. MSc. PhD. (Universidad Nacional de Asunción, Paraguay). rosa.cristaldo@gmail.com

Lider Ayala, Universidad Nacional de Asunción - Paraguay

Ing. Agr. MSc. PhD. (Universidad Nacional de Asunción, Paraguay). lider.ayala@hotmail.com

Referências

Segovia-Corrales, E; Segovia EAC

Publicado

2024-12-30

Como Citar

Segovia Corrales, E. A., Arrua, R. ., Kurita, H., Oviedo de Cristaldo, R., & Ayala, L. (2024). SAFETY ASSESSMENT OF SOYBEANS EXPOSED TO GLYPHOSATE USING IN VIVO ASSAY. La Saeta Universitaria Académica Y De Investigación, 13(2), 1–18. https://doi.org/10.56067/saetauniversitaria.v13i2.462